n. [生化]脱氢表雄(甾)酮,脱氢异雄(甾)酮


  • 1.Androgens in women either derive from direct ovarian production or from peripheral conversion of the adrenal sex steroid precursor, dehydroepiandrosterone, towards active androgens.


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  • 2.But there was also evidence that other factors contributed to sexual dysfunction, including the women's levels of DHEA, or dehydroepiandrosterone. Women with relatively low blood levels of the hormone were 59 percent more likely to report sexual problems than those with high levels.


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  • 3.In a cross-sectional study of 217 subjects, investigators examined endogenous and dehydroepiandrosterone (DHEA) levels in women with anorexia nervosa who are taking oral contraceptives (n = 32), in women with anorexia nervosa who are not taking oral contraceptives (n = 137), in normal-weight women with hypothalamic amenorrhea (n = 21), and in healthy eumenorrheic controls (n = 27)


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  • 4.In the new analysis, all of the data from these previous studies were pooled together. The team looked at blood samples taken before the men developed prostate cancer and analyzed serum concentrations of testosterone, free testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, androstenedione, androstanediol glucuronide, estradiol, and calculated free estradiol. They found no significant relation between the serum levels of any of these hormones and the risk of developing prostate cancer.


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